Home Site Map Contact Us
Rapid Learning Member Login  
Rapid Learning Blog Rapid Learning on Facebook Rapid Learning on Youtube Rapid Learning on Twitter
 How to Learn in 24 Hours?

 Need Help?
M-F: 9am-5pm(PST):
Toll-Free: (877) RAPID-10
US Direct: (714) 692-2900
Int'l: 001-714-692-2900

24/7 Online Technical Support:
The Rapid Support Center

Secure Online Order:
Buy Now


 Got Questions?
Frequently Asked Questions
 Need Proof?
Testimonials by Our Users

Trustlink is a Better Business Bureau Program.
Rapid Learning Center is a fivr-star business.

External TrustLink Reviews

 Member Login:
User ID: 

 Rapid Learning Courses:

MCAT in 24 Hours (2015-16)

USMLE in 24 Hours (Boards)

Chemistry in 24 Hours

Biology in 24 Hours

Physics in 24 Hours

Mathematics in 24 Hours

Psychology in 24 Hours

SAT in 24 Hours

ACT in 24 Hours

AP in 24 Hours

CLEP in 24 Hours

DAT in 24 Hours (Dental)

OAT in 24 Hours (Optometry)

PCAT in 24 Hours (Pharmacy)

Nursing Entrance Exams

Certification in 24 Hours

eBook - Survival Kits

Audiobooks (MP3)

Have friends taking science and math courses too? Tell them about our rapid learning system.

Home »  Biology »  Genetics

Mutation and DNA Repair

Topic Review on "Title":

DNA ass genetic material is relatively stable.  However, under many physiological conditions it may also undergo some changes.  A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence and therefore affect the function of the gene product.   Mutation can occur at either DNA or chromosome level, spontaneously or induced.

DNA mutation types
DNA mutation includes several types according to its consequence: base pair substitution (transversion or transition); missense mutation, nonsense mutation, neutral mutation, silent mutation and frame-shift mutation. 

Cause of mutation
Mutation can be spontaneous, due to the replication errors and/or chemical reactions in cells (such as depurination and deamination).  DNA mutation can also be induced by radiation and chemical mutagens. 

DNA repair mechanisms
Overall there are two classed of DNA repair mechanisms: direct repair of lesion and repair involving excision of base pairs (BER).  Direct repair includes DNA polymerase proofreading, light repair of thymidine dimers, and repair of alkylatiion damage.  BER includes excision repair, glycosylase repair, mismatch repair and SOS response. 

Rapid Study Kit for "Title":
Flash Movie Flash Game Flash Card
Core Concept Tutorial Problem Solving Drill Review Cheat Sheet

"Title" Tutorial Summary :

DNA mutation includes base pair substitution (transversion or transition); missense mutation (altered amino acid), nonsense mutation (truncated protein), neutral mutation (no phenotypical effect, similar amino acid replacement), silent mutation (with nucleotide change but amino acid remains the same) and frame-shift mutation (change all amino acid sequence after the mutation site).  DNA mutation can be spontaneous to the replication errors and/or chemical reactions in cells (such as depurination and deamination).  It can also be induced by radiation and chemical mutagens.  Mutated DNA can be repaired by various cellular mechanisms including direct repair of the lesion and repair involving excision of base pair. 

Tutorial Features:
  • Internal concept map to explain mutation and DNA repair.
  • Pictorial explanation of each class of mutations.
  • Key concept sheet and thought-provoking question sheets.
  • Chemical structure explain causes of mutations on DNA
  • Step by step diagrams and charts to show DNA repair procedure
  • Table giving DNA repair defect-caused genetic diseases

"Title" Topic List:


  • Definition
  • Levels of mutation
  • Spontaneous vs. induced
  • Base pair substitution
  • Missense mutation
  • Nonsense mutation
  • Neutral mutation
  • Silent mutation
  • Frame-shift mutation

Causes of mutations

  • Mutation rate and frequency
  • Replication erros
  • Depurination
  • Deamination
  • Radiation-induced mutation
  • Chemical-induced mutation

DNA repair

  • DNA polymerase proofreading
  • Light repair
  • Repair of akylating damage
  • Excision repair
  • Repair by glycosylase
  • Mismatch repair
  • SOS response
  • DNA repair defects and diseases

See all 24 lessons in Genetics, including concept tutorials, problem drills and cheat sheets:
Teach Yourself Genetics Visually in 24 Hours

Home »  Biology »  Genetics
© 2016 Rapid Learning Inc. All rights reserved         Disclaimer | Privacy Policy | Affiliates